Understanding Depression

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Understanding Depression

Contemporary Issues and Dilemmas

Neurology and clinical neurophysiology Psychiatry Neurosciences

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Collection: Advances in Experimental Medicine and Biology

Language: English

Published by: Springer

Published on: 26th April 2026

Format: LCP-protected ePub

ISBN: 9789819568727


Introduction

This book focuses on contemporary issues and dilemmas in relation to depression. The aim of the book is to equip readers with an up-to-date understanding of the clinical and neurobiological underpinning of depression, the clinical manifestations, and the development of more effective treatments.

Section 1: Conceptual and Diagnostic Issues

The first section discusses conceptual and diagnostic issues in major depression, highlighting current criticism and future perspective on DSM-5, biological classification, neural circuit taxonomy.

Section 2: Symptomatic and Clinical Issues

The second section considers symptomatic and clinical issues in major depression, including anhedonia, cognition, pain, suicide, obesity, and gender difference.

Section 3: Etiological and Neurobiological Issues

The third examines important etiological and neurobiological issues, including epigenetics, genetics, HPA axis, neuroimaging, and gut-brain axis.

Section 4: Therapeutic Issues

A concluding section is devoted to current therapeutic issues in major depression, focusing on new antidepressants, psychedelics, neurostimulation, digital therapy, and personalized integrative treatment.

Audience

Understanding Depression is an indispensable resource for psychiatrists, neurologists, pharmacologists, medical researchers, and graduate students engaged in affective neuroscience and clinical psychiatry.

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