Synthesis of 5-Membered Heterocycles

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Synthesis of 5-Membered Heterocycles

Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer

Biotechnology

Author: Navjeet Kaur

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Language: English

Published by: Elsevier

Published on: 12th September 2023

Format: LCP-protected ePub

ISBN: 9780443134241


Synthesis of Five-Membered Heterocycles: Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer

The book's audience, researchers, academic professionals, and synthetic chemists both in industry and academia, will find detailed information about the synthesis of five-membered heterocyclic compounds using dimethylformamide.

Over the years, heterocyclic compounds, especially five-membered, have drawn more attention from the pharmaceutical community because of their therapeutic value. The formation of heterocyclic compounds has turned out to be the keystone of synthetic organic chemistry.

Dimethylformamide has played an important role in organic synthesis for a long time, and it is frequently utilized as a common solvent for chemical reactions and broadly used in industry as a reagent. It is a unique chemical and can play three other roles in organic chemistry, i.e., as stabilizer, reagent, and catalyst. Due to its structure, DMF can participate in several reactions as a versatile building block for several units.

- Includes comprehensive descriptions of heterocycle synthesis

- Highlights many methods for the synthesis of five-membered heterocyclic compounds using dimethylformamide

- Helps readers quickly assess possible synthetic approaches

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