Practical Medicinal Chemistry with Macrocycles

Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts.

Provides needed background to build a program in macrocycle drug discovery

design criteria, macrocycle profiles, applications, and limitations

Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts

Covers design criteria, typical profile of current macrocycles, applications, and limitations