London, 2013, and the city is battling an epidemic of serial killings

even with the widespread government use of DNA detection, brain-imaging, and the ''punitive coma''.

Detective Isadora ''Jake'' Jacowicz is hunting a murderer, code-named ''Wittgenstein,'' who has taken it upon himself to eliminate anyone who has tested positive for a tendency towards violent behaviour - even if they''ve never committed a crime.

His intellectual brilliance is matched only by his homicidal madness.