Essential Guide to Neurodegenerative Disorders

Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances

Provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration.

Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich's ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches.

- Reviews big data and neurodegeneration disorders, including gene mapping

- Examines the structural basis of protein assembly into amyloid filaments in neurodegenerative disease

- Covers the progress and challenges of pharmacotherapy of neurodegenerative disorders