Introduction

This edited volume provides insights about the molecular virology, pathogenesis of infection and host responses to varicella-zoster virus, which is a medically important human herpesvirus.

Chapter Content

The chapters not only discuss genetics and molecular evolution of the virus, but also new structure-based knowledge on the functions of viral glycoproteins. Further, the authors illustrate how mechanisms from the virus are used to take over and remodel host cells during pathogenesis. These mechanisms also enable viral modulation of host cells and evasion of the host immune response. Part of these evasion and survival strategies is the reaction to triggered host cell responses like autophagy, the stress response, modulation of apoptosis and other cell death pathways.

Importance

This hands-on knowledge is crucial for students and clinicians in Virology, Immunology, and Infectious Diseases.

Open Access Notice

Chapter "Common features between stroke following varicella in children and stroke following herpes zoster in adults" is available open access under a Creative Commons Attribution 4.0 International License via Springerlink.com.