Multicellular organisms must be able to adapt to cellular events to accommodate prevailing conditions.

Sensory-response circuits operate by making use of a phosphorylation control mechanism known as the two-component system.

Sections in Two-Component Signaling Systems, Part B include:

- Structural Approaches
- Reconstitution of Heterogeneous Systems
- Intracellular Methods and Assays
- Genome-Wide Analyses of Two-Component Systems
- Presents detailed protocols
- Includes troubleshooting tips