Emergence of new and deadly infectious diseases

Emergence of new and deadly infectious diseases is significantly deteriorating human health. Development of vaccines by scientists has become an important weapon to control the spread of infectious diseases as well as to improve life expectancy at a global level in the 20th-21st Century.

About the book

This book will provide in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecules. It will cover the development of system vaccinology and their applications that revolutionize vaccine discovery. This will serve as a resource for basic and clinical researchers working to improve human life expectancy through vaccine experiments and clinical trials.

Purpose and audience

My purpose in writing this book is to educate students and researchers with modern developments in the field of vaccinology and to empower researchers with new tools and methodologies for developing potent and immunogenic vaccines. This book will help satisfy the curiosity of science and medical students related to vaccinology and assist in devising new vaccine molecules to control the spread of emerging pathogens.

Systems biology and vaccine research

Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high-throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis, we can interrogate host responses to infections and vaccination on a systems level, generating important new hypotheses and discovering unknown associations between immunological parameters.

Key highlights

• Provides in-depth knowledge of vaccine history
• Covers the development of system vaccinology and their applications that revolutionize vaccine discovery
• Gives insights into the development of new strategies to design efficacious and safe vaccine molecules
• Provides a resource for basic and clinical researchers working to improve human life expectancy through vaccine experiments and clinical trials
• Highlights the importance of differential miRNA expression and microbiome after vaccination for human health
• Serves the needs of students and researchers for applying computational tools and quickly designing potential vaccine molecules for trials
• Guides decision-making for experiments assessing vaccine immunogenicity
• Aims to understand disease pathogenesis and host responses to infection and vaccination
• Offers a seamless continuum of scientific discovery and vaccine invention