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The existence and functioning of intrinsically disordered proteins (IDPs) challenge the classical structure-function paradigm that equates function with a well-defined 3D structure.
Uncovering the disordered complement of proteomes and understanding their functioning can extend the structure-function paradigm to herald new breakthroughs in drug dev.
Intrinsically Disordered Proteins
Intrinsically Disordered Proteins
Intrinsically Disordered Protein Analysis
Protein and Peptide Folding, Misfolding, and Non-Folding
Intrinsically Disordered Protein Analysis
Intrinsically Disordered Proteins
Structure and Intrinsic Disorder in Enzymology
Dancing protein clouds: Intrinsically disordered proteins in health and disease, Part A
Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B
Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C
Three Functional States of Proteins
Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis