Solid-State Properties of Pharmaceutical Materials

£161.95

Solid-State Properties of Pharmaceutical Materials

Chemistry

Authors: Stephen R. Byrn, George Zografi, Xiaoming Chen

Dinosaur mascot

Language: English

Published by: Wiley

Published on: 17th July 2017

Format: LCP-protected ePub

Size: 24 Mb

ISBN: 9781119264453


Presenting a detailed discussion of important solid-state properties, methods, and applications of solid-state analysis

Illustrates the various phases or forms that solids can assume and discusses various issues related to the relative stability of solid forms and tendencies to undergo transformation

Covers key methods of solid state analysis including X-ray powder diffraction, thermal analysis, microscopy, spectroscopy, and solid state NMR

Reviews critical physical attributes of pharmaceutical materials, mainly related to drug substances, including particle size/surface area, hygroscopicity, mechanical properties, solubility, and physical and chemical stability

Showcases the application of solid state material science in rational selection of drug solid forms, analysis of various solid forms within drug substance and the drug product, and pharmaceutical product development

Introduces appropriate manufacturing and control procedures using Quality by Design, and other strategies that lead to safe and effective products with a minimum of resources and time

Show moreShow less