RNA Recognition, Volume 623

The latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field.

This updated volume covers a variety of topics, including:

• The Preparation of cooperative RNA recognition complexes for crystallographic structural studies
• Methods for thermal denaturation studies of fluorogenic aptamers
• Dynamic combinatorial chemistry as a rapid, fragment-based approach to RNA-targeted compound discovery
• Using a click chemistry assay to identify natural product ligands for pre-microRNAs
• Lessons from exploration of chemical and structural small molecule:RNA space
• Using ligand-observed NMR to study RNA-small molecule interactions
• And much more

Provides the authority and expertise of leading contributors from an international board of authors

Presents the latest release in the Methods in Enzymology series

Includes the latest information on RNA Recognition