Recent Trends in Carbohydrate Chemistry: Synthesis and Biomedical Applications of Glycans and Glycoconjugates

covers biomedically relevant bacterial cell wall carbohydrates including recent findings on biosynthetic aspects, advances in the chemical assembly of bacterial lipopolysaccharide fragments and teichoic acids, and modern NMR approaches to unravel structural details. The first part introduces and provides the relevant background for synthetic glycoconjugate vaccines. The second section focuses on synthetic carbohydrate-based vaccines of therapeutic potential that are licensed or under development.

This second volume of Recent Trends in Carbohydrate Chemistry is ideal for researchers working as synthetic organic chemists, as well as those interested in glycoconjugation, protein chemists, immunologists, and microbiologists, in academia as well as in industry.

Highlights

important features of bacterial glycoproteins

Illustrates modern chemical synthesis and structural analysis of bacterial glycans

Demonstrates the importance of carbohydrate chemistry for the synthesis of lipopolysaccharides and teichoic acid

Covers recent findings on glycan ligation

Gives an overview of the most recent developments on carbohydrate-based vaccines