Rearrangements with Migration to Electrophilic Heteroatomic Centers

Timeless Classics in Organic Synthesis covers the basic principles and synthetic applications of a critically important class of organic reactions that date back to the founding period of organic chemistry. These reactions are not only of historical and pedagogical interest, but also have great practical value to this day, being inevitable in any strategy concerning the introduction of nitrogen and oxygen functionality.

The book is made up of three parts, dealing with the Beckmann reaction, the Hoffmann family of reactions and the Baeyer-Villiger reaction. The book strikes a balance between delineation and exhaustiveness, with up-to-date references for readers requiring in-depth coverage. Relevant industrial applications, including pharmaceutical processes, are included.

Key Features

- Summarizes mechanistic background with an emphasis on synthetic applications

- Includes up-to-date references that allow for locating original papers for experimental procedures

- Provides applications in the synthesis of complex molecules and natural products to judge the scope and limitations of each reaction