Realisation of Quadruplex Structures in Genomes

The realisation that human, animal, viral, and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes.

Therapeutic and Diagnostic Potential

Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.

Authoritative Insights

Provides the authority and expertise of leading contributors from an international board of authors

Latest Series Release

Presents the latest release in the Annual Reports in Medicinal Chemistry series