The field of proteomics

The field of proteomics moves rapidly. New methods, techniques, applications, standards, models, and software appear almost on a daily basis. Accompanying this are plenty of texts on the experimental side of the field and a few appearing on the informatic and data analysis side. This latterly includes one in the Methods in Molecular Biology series tackling the specific analysis of “Mass spectrometry data in proteomics” in MMB vol. 376.

Current collection and scope

This current collection builds on this, but takes a broader view of proteome data analysis covering data analysis essentials, but also the databases and data models, as well as practical considerations for analysing database search results, annotating genomes, and speeding up searches. It also digs deeper into some topics, such as decoy database searching and aspects of signal processing in proteomic mass spectrometry.

Volume aim

The aim of the volume is to provide the reader with a mix of reviews and methodology chapters, which build from the essentials of database searching in proteomics, on through specific data processing challenges to databases, data standards, and data models.