This book presents best-selected papers presented at the 5th International Conference on Emerging Trends and Technologies on Intelligent Systems (ETTIS 2025) held from 19 - 21 March 2025 in hybrid mode at C-DAC, Noida, India. The book includes current research works in the areas of artificial intelligence, big data, cyber-physical systems, and security in industrial/real-world settings. The book illustrates on-going research results, projects, surveying works, and industrial experiences that describe significant advances in all of the related areas.