Posttraumatic Epilepsy: Basic and Clinical Aspects

Provides a synthesized resource on the recent basic and clinical science developments in the field of posttraumatic epilepsy. This book provides a clear understanding of the history of studies and epidemiology of posttraumatic epilepsy after head injury. The book also considers the neuropathology of posttraumatic epilepsy and clinical trials of antiepileptogenic agents evaluated after traumatic brain injury. The book covers the basic science of animal models of traumatic brain injury and the necessary and sufficient changes that must occur to generate epilepsy after head trauma. The authors explore potential mechanisms and novel therapeutic approaches to prevent posttraumatic epilepsy. The book is written for basic and clinical researchers in neuroscience as well as for clinicians treating patients with epilepsy.

Reviews the history and epidemiology of posttraumatic epilepsy

Considers the neuropathology of posttraumatic epilepsy

Synthesizes studies demonstrating risk factors for susceptibility to epilepsy after head trauma

Reviews animal models of traumatic brain injury

Addresses our current understanding of mechanisms of posttraumatic epilepsy

Explores novel therapeutic approaches to prevent posttraumatic epilepsy