Microbial biofilms: Role in Human Infectious Diseases

Focuses on new and emerging concepts in microbial biofilm research, such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections.

In addition, it highlights the various anti-biofilm strategies such as surface coating, signal quenching, and novel compounds that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.

Microbial biofilms can be a serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms increases recovery time and the cost of disease management. Biofilms are resistant to known antibiotics and human defense mechanisms. In addition, due to the close proximity of microbes within biofilms, increased genetic transformation has been detected, resulting in increased frequency of antibiotic gene spread.

With the advancement in science and technology, novel strategies have been proposed to combat the impact of biofilms on human health.

- Fulfills the knowledge gap in biofilm study

- Focuses on new and emerging concepts in microbial biofilm research

- Highlights the various anti-biofilm strategies

- Provides concise, thorough, and up-to-date information about the important role of microbial biofilms in human diseases