£112.50
Metastasis Research Protocols
Volume I: Analysis of Cells and Tissues
We presented a range of protocols aimed at mapping and analyzing the expression of various molecules of potential interest in metastasis research and for examining their production at the genetic level.
Second Volume of Metastasis Research Protocols
We move to the level of living cells and tissues and present methodologies applicable to examining metastatic behavior in vitro and in whole animal models.
Methods in the First Section
The methods described in the first section of this volume concentrate on the separation of cell lines with high and low metastatic potential, including the genetic modification of cell lines.
Assay Systems in Part II
The assay systems to test defined aspects of the metastatic cascade are then described in Part II and include cell migration assays, assays for matrix degrading enzymes, basement membrane degrading assays, adhesion assays, and assays of angiogenesis.
Role of Metastatic Cascade Elements
The role of the specific elements of the metastatic cascade assayed in each of these systems in turn must of course be put into perspective relative to their roles in entire living organisms.
