Elizabeth Epona Pendergass lives a privileged life. She attends a strict private school, is driven by a chauffeur, and takes riding lessons. Grandmother and Grandfather Pendergass were from one of the oldest families of Boston, tracing their family tree back to England, where they were distantly related to royalty.

But Elizabeth maintains a sweet, unspoiled spirit of obedience, even if it goes against everything she thinks or wants. Her love of horses drives most everything she does. As the school year ends in the city, Elizabeth looks forward to spending her summer with her grandparents in Kentucky while her parents tour Europe again.

Lizzy N Dizzy follows Elizabeth on a summer journey that leads her to a new relationship with her blue-blooded grandparents and, eventually, her parents. It shares how her love of horses makes all this possible, along with some new friends, like Jed and DIZ, she meets along the way.