Introduction to Leukemia Stem Cells

This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies. It addresses the role of leukemia stem cells in different leukemia diseases and molecular signatures, as well as the metabolic and epigenetic regulation of leukemia stem cell function.

Leukemia Stem Cells and Solid Tumors

With regard to solid tumors, a significant number of blood cancers are believed to be derived from leukemia stem cells (LSCs), which are responsible for disease progression, relapse, and drug resistance. Consequently, new therapeutic strategies need to be developed by focusing on the complete eradication of LSCs.

Target Audience and Scope

Given its scope, the book offers a valuable asset for graduate students and scientists in the fields of cell biology and cancer research.