Information Geometry and Population Genetics

£109.50

Information Geometry and Population Genetics

The Mathematical Structure of the Wright-Fisher Model

Medical genetics Calculus and mathematical analysis Geometry Probability and statistics Stochastics Computational biology / bioinformatics

Authors: Julian Hofrichter, Jurgen Jost, Tat Dat Tran

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Collection: Understanding Complex Systems

Language: English

Published by: Springer

Published on: 23rd February 2017

Format: LCP-protected ePub

Size: 4 Mb

ISBN: 9783319520452


Overview

The present monograph develops a versatile and profound mathematical perspective of the Wright--Fisher model of population genetics. This well-known and intensively studied model carries a rich and beautiful mathematical structure, which is uncovered here in a systematic manner.

Approaches and Perspectives

In addition to approaches by means of analysis, combinatorics and PDE, a geometric perspective is brought in through Amari's and Chentsov's information geometry. This concept allows us to calculate many quantities of interest systematically; likewise, the employed global perspective elucidates the stratification of the model in an unprecedented manner.

Connections and Applications

Furthermore, the links to statistical mechanics and large deviation theory are explored and developed into powerful tools. Altogether, the manuscript provides a solid and broad working basis for graduate students and researchers interested in this field.

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