How to Design and Implement Powder-to-Tablet Continuous Manufacturing Systems

Provides a comprehensive overview on the considerations necessary for the design of continuous pharmaceutical manufacturing processes. The book covers both the theory and design of continuous processing of associated unit operations, along with their characterization and control. In addition, it discusses practical insights and strategies that the editor and chapter authors have learned. Chapters cover Process Analytical Technology (PAT) tools and the application of PAT data to enable distributed process control.

With numerous case studies throughout, this valuable guide is ideal for those engaged in, or learning about, continuous processing in pharmaceutical manufacturing.

Discusses the development of strategy blueprints in the design of continuous processes

Shows how to create process flowsheet models from individual unit operation models

Includes a chapter on characterization methods for materials, the use of statistical methods to analyze material property data, and the use of material databases

Covers the evolving regulatory expectations for continuous manufacturing

Provides readers with ways to more effectively navigate these expectations