Introduction

The goal of this text is to focus readers' attention on three major areas; the origin and localization of GSH in the nervous system; the multiple effects of GSH on neural health activity; and the potential for alterations on GSH status to lead to neurological damage of the type observed in amyotrophic lateral sclerosis, Parkinson's disease, and other neurological disorders.

The text also touches upon the additional roles of the antioxidant GSH, including possible neurotransmitter action, redox modulation of ionotropic receptor function, and neuroprotection against excitotoxic actions of glutamate.