Genetics and Neurobiology of Down Syndrome

Provides a thorough review of the genetic etiology and mechanisms of trisomy 21. The author discusses the history of the syndrome, along with the clinical features and health consequences, including physical features, cognitive, and neurologic symptoms. Genetic counseling on pros and cons of prenatal screening and testing and associated ethical issues are explored. This unique book also covers the societal and demographic aspects as well as the future direction of therapeutic development.

Reviews genetic etiology and mechanisms of trisomy 21

Discusses prenatal screening and genetic counseling, including ethical aspects

Explores link between Down Syndrome and susceptibility to Alzheimer’s and early brain aging

Covers cognitive and neurological symptoms and other health consequences

Identifies future therapeutic developments