With a focus on functional relationships between drugs and their targets

This book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use – without neglecting clinical application, toxicology, and pharmacokinetics.

Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students

Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs

Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties

Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development

Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, and all figures and tables from the book