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It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing.
This new text asks the question, "How can we use computational method"
Computer Applications in Drug Discovery and Development
Drug Development Supported by Informatics
Computational Approaches in Drug Discovery, Development and Systems Pharmacology
Computational Methods for Drug Repurposing
Computational Methods in Biomedical Research
Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design
Computational Drug Discovery and Design
Drug Discovery and Evaluation: Methods in Clinical Pharmacology
Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays
Biomedical Applications of Computer Modeling
Pre-Clinical Models
Statistical Methods in Biomarker and Early Clinical Development