Cellular Senescence and Brain Aging

£89.50

Cellular Senescence and Brain Aging

Mechanisms, Therapeutic Strategies, and Implications for Neurodegenerative Diseases

Immunology Neurosciences Cellular and molecular neuroscience

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Language: English

Published by: Springer

Published on: 12 August 2025

Format: LCP-protected ePub

ISBN: 9789819688739


Overview

The book examines the cellular senescence in brain aging processes and its effects on three major neurodegenerative conditions: Alzheimer's disease, Parkinson's disease, and Huntington's disease. It discusses basic aging mechanisms, including oxidative stress, mitochondrial dysfunction, and neuroinflammation, before moving on to current treatments such as senolytics and autophagy modulators.

Structure

The book is divided into several chapters, with specific sections dedicated to experimental approaches, detection methods, and disease-by-disease analysis of cellular senescence effects. A specific chapter explores the clinical potential of senescence-targeting therapies and discusses upcoming study pathways.

Intended Audience

This publication is aimed at researchers in neuroscience, clinicians, graduate students, neuroscientists, and neuropharmacology professionals involved in the assessment of age-related disorders. It delivers thorough expertise by combining research evidence on brain aging with methods to combat cognitive decline. The structured system within this publication creates connections between basic research and medical implementation, providing essential knowledge for treating neurodegeneration.

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