Cell Movement in Health and Disease

Brings the several scientific domains related to the phenomena together, establishing a consistent foundation for researchers in this exciting field. The content is presented in four main sections. The first explores the foundations of Cell Movement, including overviews of cellular structure, signaling, physiology, motion-related proteins, and the interface with the cellular membrane.

The second part covers the biological aspects of cellular movement, starting with chemical and mechanical sensing, describing the types of cell movement, mechanics at the cell level, cell physiology, collective behavior, and the connections with the extracellular matrix. The following chapters provide an overview of the molecular machinery involved and cell-type specific movement.

The third part of the book is dedicated to the translational aspects of cell movement, highlighting the key conditions associated with cell movement dysfunction, like cell invasion in cancer, wound healing, developmental issues, neurological dysfunctions, and immune response.

The final part of the book covers key methods and modeling tools for cell movement research, including predictive mathematical models, in vitro and in vivo methods, biophysical and bioinformatics tools.

Cell Movement in Health and Disease is the ideal reference for scientists from different backgrounds converging to expand the understanding of this key cellular process. Cellular and molecular biologists will gain a better understanding of the physical principles operating at the cellular level while biophysicists and biomedical engineers will benefit from the solid biology foundation provided by the book.

- Combines Biology, Physics and Modeling of cellular movement in one single source

- Updated with the current understanding of the field

- Includes key research methods for cell movement investigation

- Covers translational aspects of cellular movement