This book constitutes the refereed proceedings of the 8th International Workshop on Biomedical Image Registration, WBIR 2018, held in Leiden, The Netherlands, in June 2018.

The 11 full and  poster papers included in this volume were carefully reviewed and selected from 17 submitted papers. The papers are organized in the following topical sections: Sliding Motion, Groupwise Registration, Acceleration, and Applications and Evaluation.