The Biology of Ageing: From Hallmarks to Drugs

Provides a series of reviews covering multiple aspects of the translational pipeline as interventions in the biology of ageing itself become a clinical reality. New chapters cover Cellular senescence and NAD+: what are the links?, Biomarker for ageing: potential and pitfalls, What chemists offer to ageing research, You are what you eat – or are you? Exploring dietary versus topical anti-oxidants in skin ageing, Clinical trials: A simple guide for gerontologists, Towards an ethical framework for geroscience, and more.

The book explores links between known ageing mechanisms and new interventions, agents and actions at the nutraceutical-drug divide, the challenges and opportunities provided by biomarkers and chemistry-biology interface and lastly the ethical and operational challenges of clinical trials in the age of translational geroscience.

— Covers novel mechanistic ideas

— Includes ethical and industrial input

— Focuses on problems and solutions from chemistry and biomarkers to the clinic