In the first decades of the 1800s, white Americans entered the rugged lands of Arkansas, which they had little explored before. They established new towns and developed commercial enterprises alongside Native Americans indigenous to Arkansas and other tribes and nations that had relocated there from the East.

This history is also the story of Arkansas's people, and is told through numerous biographies, highlighting early life in frontier Arkansas over a period of 200 years. The book provides a categorical look at commerce and portrays the social diversity represented by both prominent and common Arkansans--all grappling for success against extraordinary circumstances.